Surgical Prep - Wound Site Preparation

July 4th, 2009
  • There are several products in the pharmaceutical marketplace that are spread on / around a wound site prior to surgery ( eg Chloraprep, Duraprep). Their purpose is to kill bacteria. And they contain antimicrobials to achieve this. How large a marketplace is this (US only) in terms of dollars spent specifically on surgical preps for wound site preparation? What are the different surgical preps in the marketplace - specifically for wound site preparation?


  • Hello again Superg327, I have been working on your question and although I was not able to locate dollar figures, I did uncover some relevant information for you. Please let me know via the CLARIFICATION feature if my findings would serve your purpose and I will post them as your official answer. Sincerely, Bobbie7 ------------------------------------------------- Patient preoperative solutions containing alcohol DuraPrep, 26 ml 6,000,000 units estimated sold annually ChloraPrep, 10.5 ml 1,500,000 units estimated sold annually Cardinal Large Applicators (Prevail, 59 m; Prevail FX, 40 ml) 1,500,000 units estimated sold annually FDA http://www.fda.gov/ohrms/dockets/dailys/04/nov04/113004/04p-0528-cp00001-vol1.pdf ------------------------------------------------- "There are approximately 60 million inpatient and ambulatory surgical procedures performed in the U.S. annually" Sage http://www.sageproducts.com/lit/20778.pdf http://www.sageproducts.com/products/ssi.asp ================ Product listings ================ The first line is the name of the Company, the second line is the product and the third line is the active ingredient. Healthpoint Actiprep Preoperative Skin Preparation Trizenol - alcohol w/ preservative, emollients Purdue Pharma Betadine Solution 10% povidone iodine Alcon Labs BETADINE 5% Sterile Ophthalmic Prep Solution povidone iodine Medi-Flex, Inc. ChloraPrep One-Step chlorhexidine gluconate 2% w/v; Isopropyl alcohol Aplicare Chlorhexidine Gluconate, 2% and 4% Chlorhexidine Gluconate Kendall Company Curity Alcohol Preps 70% isopropyl alcohol 3M DuraPrep Surgical Solution 74% isopropyl alcohol, 0.7% iodine Regent Medical Hibiclens chlorhexidine gluconate Aplicare Povidone Iodine Prep 10% and Scrub, 7.5% presaturated on single and triple swabsticks Povidone Iodine Aplicare Povidone Iodine Prep and Scrub Solutions presaturated on 8" Pain Sticks and Winged Sponges Povidone Iodine Dynarex Corporation Povidone Iodine Prep Solution 10% povidone iodine Aplicare Povidone Iodine Prep, 10% and Scrub, 7.5% Solutions Povidone Iodine Dynarex Corporation PVP Prep Pads 10% povidone iodine Medline PVP Prep Solution 10% povidone iodine Cardinal Health Scrub Care Exidine 2% & 4% Chlorhexidine Gluconate chlorhexidine gluconate Cardinal Health Scrub Care Povidone-Iodine Cleansing & Topical Solutions povidone iodine Cardinal Health Scrub Care Prevail One-Step Preoperative Prep Gel povidone iodine, isopropyl alcohol Cardinal Health Scrub Care Prevail-Fx One-Step Preoperative Prep Solutions povidone iodine, isopropyl alcohol Care-Tech Techni-Care Antiseptic Prep chloroxylenol 3%, dimonium chloride phosphate 2% Healthpoint Triseptin Hand & Body Antiseptic Trizenol - alcohol w/ preservatives, emollients Kendall Company Webcol Alcohol Preps 70% isopropyl alcohol http://www.outpatientsurgery.net/surgical_supplies/products/patient_preps.php?sortBy=product&orderBy=ASC -------------------------------------------------------- One-Step Prep "3M brand One-Step Patient Prep, a povidone iodine-based patient preoperative skin prep, delivered in a single-use sterile applicator. The alcohol-free solution can be used on both skin and mucous membranes." "Preoperative skin preparation serves as a front line defense against surgical site infection," said James Ingebrand, business director, 3M Medical Division "Key Drivers of Innovation to the Patient Prep Market Identified by Surgeons and Operating Room Nurses: -- Reduced application time -- Antimicrobial activity after exposure to blood and saline -- Enhanced surgical drape adhesion -- Sterile, easy delivery " http://www.findarticles.com/p/articles/mi_m0EIN/is_2005_April_5/ai_n13505643 http://www.bioportfolio.com/april_05/06_04_2005/3M_Health_Care_Improves.html "Actiprep?, a patient preoperative preparation solution, is a one-step prep that features Trizenol? technology with a film-former and a dye." http://www.infectioncontroltoday.com/articles/161feat5.html "Chlorascrub Swabstick and Chlorascrub Maxi Swabstick are approved for patient preoperative skin preparation. Chlorascrub Swab, Chlorascrub Swabstick, and Chlorascrub Maxi Swabstick are approved for patient pre-injection preparation. These latex-free products help reduce bacteria that potentially can cause skin infection." http://www.pharmalive.com/magazines/medad/view.cfm?articleID=3029


  • Superg327, I was wondering if you had a chance to review my findings? Thanks, Bobbie7


  • Yes that will suffice - thank you.


  • Dear Superg327, Thank you for the positive response to my clarification. I am posting the information below to make this answer official. Sincerely, Bobbie7 ------------------------------------------------- Patient preoperative solutions containing alcohol DuraPrep, 26 ml 6,000,000 units estimated sold annually ChloraPrep, 10.5 ml 1,500,000 units estimated sold annually Cardinal Large Applicators (Prevail, 59 m; Prevail FX, 40 ml) 1,500,000 units estimated sold annually FDA http://www.fda.gov/ohrms/dockets/dailys/04/nov04/113004/04p-0528-cp00001-vol1.pdf ------------------------------------------------- "There are approximately 60 million inpatient and ambulatory surgical procedures performed in the U.S. annually" Sage http://www.sageproducts.com/lit/20778.pdf http://www.sageproducts.com/products/ssi.asp ================ Product listings ================ The first line is the name of the Company, the second line is the product and the third line is the active ingredient. Healthpoint Actiprep Preoperative Skin Preparation Trizenol - alcohol w/ preservative, emollients Purdue Pharma Betadine Solution 10% povidone iodine Alcon Labs BETADINE 5% Sterile Ophthalmic Prep Solution povidone iodine Medi-Flex, Inc. ChloraPrep One-Step chlorhexidine gluconate 2% w/v; Isopropyl alcohol Aplicare Chlorhexidine Gluconate, 2% and 4% Chlorhexidine Gluconate Kendall Company Curity Alcohol Preps 70% isopropyl alcohol 3M DuraPrep Surgical Solution 74% isopropyl alcohol, 0.7% iodine Regent Medical Hibiclens chlorhexidine gluconate Aplicare Povidone Iodine Prep 10% and Scrub, 7.5% presaturated on single and triple swabsticks Povidone Iodine Aplicare Povidone Iodine Prep and Scrub Solutions presaturated on 8" Pain Sticks and Winged Sponges Povidone Iodine Dynarex Corporation Povidone Iodine Prep Solution 10% povidone iodine Aplicare Povidone Iodine Prep, 10% and Scrub, 7.5% Solutions Povidone Iodine Dynarex Corporation PVP Prep Pads 10% povidone iodine Medline PVP Prep Solution 10% povidone iodine Cardinal Health Scrub Care Exidine 2% & 4% Chlorhexidine Gluconate chlorhexidine gluconate Cardinal Health Scrub Care Povidone-Iodine Cleansing & Topical Solutions povidone iodine Cardinal Health Scrub Care Prevail One-Step Preoperative Prep Gel povidone iodine, isopropyl alcohol Cardinal Health Scrub Care Prevail-Fx One-Step Preoperative Prep Solutions povidone iodine, isopropyl alcohol Care-Tech Techni-Care Antiseptic Prep chloroxylenol 3%, dimonium chloride phosphate 2% Healthpoint Triseptin Hand & Body Antiseptic Trizenol - alcohol w/ preservatives, emollients Kendall Company Webcol Alcohol Preps 70% isopropyl alcohol http://www.outpatientsurgery.net/surgical_supplies/products/patient_preps.php?sortBy=product&orderBy=ASC -------------------------------------------------------- One-Step Prep "3M brand One-Step Patient Prep, a povidone iodine-based patient preoperative skin prep, delivered in a single-use sterile applicator. The alcohol-free solution can be used on both skin and mucous membranes." "Preoperative skin preparation serves as a front line defense against surgical site infection," said James Ingebrand, business director, 3M Medical Division "Key Drivers of Innovation to the Patient Prep Market Identified by Surgeons and Operating Room Nurses: -- Reduced application time -- Antimicrobial activity after exposure to blood and saline -- Enhanced surgical drape adhesion -- Sterile, easy delivery " http://www.findarticles.com/p/articles/mi_m0EIN/is_2005_April_5/ai_n13505643 http://www.bioportfolio.com/april_05/06_04_2005/3M_Health_Care_Improves.html "Actiprep?, a patient preoperative preparation solution, is a one-step prep that features Trizenol? technology with a film-former and a dye." http://www.infectioncontroltoday.com/articles/161feat5.html "Chlorascrub Swabstick and Chlorascrub Maxi Swabstick are approved for patient preoperative skin preparation. Chlorascrub Swab, Chlorascrub Swabstick, and Chlorascrub Maxi Swabstick are approved for patient pre-injection preparation. These latex-free products help reduce bacteria that potentially can cause skin infection." http://www.pharmalive.com/magazines/medad/view.cfm?articleID=3029







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